What is Chronic Myeloid Leukaemia (CML)?

Chronic Myeloid Leukaemia (CML) is a form of leukaemia where you have an increase in your white blood cells.

In CML, your bone marrow (the spongey part inside your bones) is producing too many myeloid cells, which are underdeveloped white blood cells that don’t work properly.

CML often develops slowly over several years, and is most common in people aged between 60 – 65.

Roughly, CML makes up 15 out of 100 leukaemia cases.

Symptoms and Diagnosis of CML

The majority of CML patients are asymptomatic, meaning little to no symptoms, and CML is only picked up through a blood test from their GP.

For some, where they have a much higher count of white blood cells, some patients experience:
– pain from an enlarged spleen
– Anemia
– Tiredness
– Bone pains

Treatment For CML

Treatment depends on if you’re asymptomatic or have a very high white blood cell count.

If you have a very high blood count, you could be put on a special machine that helps to skim off some of the extra white blood cells.

You could also be given medication to control and bring the white blood cell count down.

Side effects for treatment 

The majority of patients receiving treatment for CML will often have very mild side effects.

Some side effects could include:

– aches and pains in your muscles
– face swelling
– rashes
– Indigestion

Clinical Trials For CML


There are trials looking at how to stop therapy and who can stop and who can’t.
There are also studies looking at new drugs and treatments, especially for those patients who aren’t responding as well to the currently drugs as others.


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